4-Hydroxyphthalic anhydride
5-hydroxy-2-benzofuran-1,3-dione
CAS: 27550-59-0
Molecular Formula: C8H4O4
4-Hydroxyphthalic anhydride - Names and Identifiers
4-Hydroxyphthalic anhydride - Physico-chemical Properties
| Molecular Formula | C8H4O4 |
| Molar Mass | 164.12 |
| Density | 1.624±0.06 g/cm3(Predicted) |
| Melting Point | 171-173 °C(Solv: acetic acid (64-19-7)) |
| Boling Point | 407.8±28.0 °C(Predicted) |
| pKa | 6.52±0.20(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
4-Hydroxyphthalic anhydride - Introduction
5-hydroxy-2-benzofuran-1,3-dione is an organic compound with the chemical formula C8H4O4, also known as 5-hydroxymangosterone.
Nature:
5-hydroxy-2-benzofuran-1,3-dione is a white crystalline solid. It is soluble in alcohols, ketones and ethers at room temperature, and insoluble in water. It has a strong smell of phenol.
Use:
5-hydroxy-2-benzofuran-1,3-dione is widely used in organic synthesis and medicinal chemistry. It can be used as an important intermediate in organic synthesis, and has a wide range of applications in the synthesis of dyes, drugs and pesticides.
Preparation Method:
5-hydroxy-2-benzofuran-1,3-dione can be prepared by various methods, for example, by reacting phenol with chloroacetic acid under acidic conditions. In addition, there are other synthetic methods, such as the use of substituted phenols and carbonyl compounds for the synthesis of diazo compounds, one-step synthesis from tannins and so on.
Safety Information:
5-hydroxy-2-benzofuran-1,3-dione is generally stable when used and stored correctly, but it may cause irritation to the eyes, skin and respiratory tract. Therefore, protective gloves, goggles and protective mask should be worn during operation to avoid contact with skin and inhalation. At the same time, make sure to operate under well-ventilated conditions.
Nature:
5-hydroxy-2-benzofuran-1,3-dione is a white crystalline solid. It is soluble in alcohols, ketones and ethers at room temperature, and insoluble in water. It has a strong smell of phenol.
Use:
5-hydroxy-2-benzofuran-1,3-dione is widely used in organic synthesis and medicinal chemistry. It can be used as an important intermediate in organic synthesis, and has a wide range of applications in the synthesis of dyes, drugs and pesticides.
Preparation Method:
5-hydroxy-2-benzofuran-1,3-dione can be prepared by various methods, for example, by reacting phenol with chloroacetic acid under acidic conditions. In addition, there are other synthetic methods, such as the use of substituted phenols and carbonyl compounds for the synthesis of diazo compounds, one-step synthesis from tannins and so on.
Safety Information:
5-hydroxy-2-benzofuran-1,3-dione is generally stable when used and stored correctly, but it may cause irritation to the eyes, skin and respiratory tract. Therefore, protective gloves, goggles and protective mask should be worn during operation to avoid contact with skin and inhalation. At the same time, make sure to operate under well-ventilated conditions.
Last Update：2024-04-09 21:11:58
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